Study information
Patients in this study received a diagnosis of early-stage or locally advanced breast cancer and were recommended to receive neoadjuvant chemotherapy as their initial treatment prior to surgery.
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Participants had 6-8 cycles of chemotherapy that were typically 2-3 weeks apart. Prior to each cycle of chemotherapy, each breast was scanned with the imaging system.​​​​
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Treatment-related information was compiled for the participants (e.g. screening mammogram, diagnostic mammogram, ultrasound, imaging reports, biopsy dates and results, chemotherapy treatment protocol, dates of treatment, mid- and end-point imaging and reports, surgery and post-surgical pathology).​
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The study was approved by the Health Research Ethics Board of Alberta - Cancer Committee (HREBA.CC-22-0333).
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Sample results
Case studies are shown for patients with breast densities C and D.
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Mammograms are shown on the left for each case study, followed by the series of UWB images collected before each cycle of chemotherapy.
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Images for both breasts are presented. "C" indicates the breast with cancer, while "H" denotes the healthy breast.
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Case study 1: Patient had breast density of D, and invasive ducal carcinoma of extent 2.6 x 1.6 x. 1.5 cm in her left breast. Mid-point imaging showed a marked reduction in tumor size, while post-surgical pathology indicated a complete response to treatment.
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Case study 2: Patient had breast density of C, and invasive ducal carcinoma of 2.2 x 1.2 x. 1.5 cm in her left breast. Mid-point imaging showed a decreased size, while post-surgical pathology indicated a good partial response to treatment.
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Additional case studies and analysis are available in Mojabi e al, Point-of-care breast imaging for monitoring neoadjuvant treatment: case studies with transmission-based microwave imaging. IEEE Transactions on Biomedical Engineering, 2025.
Figures on this page © 2025 IEEE. All rights reserved, including rights for text and data mining and training of artificial intelligence and similar technologies. Reprinted with permission from Mojabi et al, Point-of-care breast imaging for monitoring neoadjuvant treatment: case studies with transmission-based microwave imaging. IEEE Transactions on Biomedical Engineering, 2025.