Study information
Patients in this study received a diagnosis of early-stage or locally advanced breast cancer and were recommended to receive neoadjuvant chemotherapy as their initial treatment prior to surgery.
Participants had 6-8 cycles of chemotherapy that were typically 2-3 weeks apart. Prior to each cycle of chemotherapy, each breast was scanned with the imaging system.
Treatment-related information was compiled for the participants (e.g. screening mammogram, diagnostic mammogram, ultrasound, imaging reports, biopsy dates and results, chemotherapy treatment protocol, dates of treatment, mid- and end-point imaging and reports, surgery and post-surgical pathology).
The study was approved by the Health Research Ethics Board of Alberta - Cancer Committee (HREBA.CC-22-0333).
Sample results
Case studies are shown for patients with breast densities C and D.
Mammograms are shown on the left for each case study, followed by the series of UWB images collected before each cycle of chemotherapy.
Images for both breasts are presented. "C" indicates the breast with cancer, while "H" denotes the healthy breast.
Case study 1: Patient had breast density of D, and invasive ducal carcinoma of extent 2.6 x 1.6 x. 1.5 cm in her left breast. Mid-point imaging showed a marked reduction in tumor size, while post-surgical pathology indicated a complete response to treatment.
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Case study 2: Patient had breast density of C, and invasive ducal carcinoma of 2.2 x 1.2 x. 1.5 cm in her left breast. Mid-point imaging showed a decreased size, while post-surgical pathology indicated a good partial response to treatment.
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Additional case studies and analysis are available in Mojabi e al, Point-of-care breast imaging for monitoring neoadjuvant treatment: case studies with transmission-based microwave imaging. IEEE Transactions on Biomedical Engineering, 2025.
Figures on this page © 2025 IEEE. All rights reserved, including rights for text and data mining and training of artificial intelligence and similar technologies. Reprinted with permission from Mojabi et al, Point-of-care breast imaging for monitoring neoadjuvant treatment: case studies with transmission-based microwave imaging. IEEE Transactions on Biomedical Engineering, 2025.